Global Scans · chromosonal · Weekly Summary

• The RGMb Antisense RNA 1 gene is located on human chromosome 5 q21.1, and its transcription product is lncRNA RGMb-AS1 with a length of 2053 bp. Cambridge Core
• DNA Futures are leading the development of a UK Y-chromosome reference database that will enable the estimation of the frequency of Y-STR profiles specifically in the UK population. GOV.UK
• In multiple studies presented at 2025's EHA Annual Congress, the third-generation tyrosine kinase inhibitor olverembatinib showed broad therapeutic potential and demonstrated particular clinical benefit in the treatment of Philadelphia chromosome-positive acute lymphoblastic leucaemia. ASCENTAGE PHARMA GROUP INTERNATIONAL
• Increasing Indigenous American chromosomal copy at 6 q25 reduced Bca risk, while increasing European chromosomal copy increased Bca risk. PubMed Central (PMC)
• The virtual population consisted of 100000 singleton pregnant women, who have similar characteristics to Quebec's pregnant women aged 14-49 years in terms of age distribution and risk for a fetal chromosomal anomaly. BMJ Open
• The dominant indirect effect of low LET irradiation is mainly induced through water radiolysis products, which can cause DNA breaks and complex chromosomal aberrations, protein denaturation, cell membrane disruption, enzyme inactivation, and DNA or RNA mutations. Nickel
• With expanded NIPT, healthcare providers can obtain a comprehensive view of all 23 chromosome pairs while limiting risk to their patient. / Thailand Illumina
• AB8939 intellectual property rights in AML are secured until 2036 through a 'composition of matter' patent and potentially until 2044 in AML with chromosome abnormality, including MECOM, through a 'second medical use' patent. MarketScreener

Last updated: 19 October 2025